Bioorthogonal Metalloporphyrin‐Catalyzed Selective Methionine Alkylation in the Lanthipeptide Nisin
نویسندگان
چکیده
منابع مشابه
The Selective N-Alkylation of Monoethanolamine
Alkyl derivatives of MEA are used in the production of surfactants, dyes, in the manufacture of drugs as a buffer substance and for the stabilization of emulsions, in the manufacture of herbicides, cosmetics, antihistamines, are also of practical interest [1]. It is widely known also as useful “acid” gases (H2S, CO2, SO2, etc.) as absorbents in the process of cleaning process for gases in oil r...
متن کاملThe Selective N-Alkylation of Monoethanolamine
Alkyl derivatives of MEA are used in the production of surfactants, dyes, in the manufacture of drugs as a buffer substance and for the stabilization of emulsions, in the manufacture of herbicides, cosmetics, antihistamines, are also of practical interest [1]. It is widely known also as useful “acid” gases (H2S, CO2, SO2, etc.) as absorbents in the process of cleaning process for gases in oil r...
متن کاملEvolution of lanthipeptide synthetases.
Lanthionine-containing peptides (lanthipeptides) are a family of ribosomally synthesized and posttranslationally modified peptides containing (methyl)lanthionine residues. Here we present a phylogenomic study of the four currently known classes of lanthipeptide synthetases (LanB and LanC for class I, LanM for class II, LanKC for class III, and LanL for class IV). Although they possess very simi...
متن کاملAlkylation of the Methionine Residues of Ribonuclease in 8 M Urea.
The identity of some of the amino acid residues at the active site of ribonuclease is now known (see Crestfield, Stein, and Moore (1) for references and discussion) and the availability of other functional groups in the molecule has been studied extensively. For example, Anfinsen, Sela, and Cooke (2) have investigated the reduction and reoxidation of disulfide bonds in polyalanyl ribonuclease a...
متن کاملControlling release from the lipidic cubic phase by selective alkylation.
The lipidic cubic phase can be viewed as a molecular sponge consisting of interpenetrating nanochannels filled with water and coated by lipid bilayers. It has been used as a delivery matrix for low-molecular-weight drugs. For those that are water-soluble, release is fast and unregulated. This study seeks to exploit the lipid bilayer compartment as a location within the cubic phase in which to '...
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ژورنال
عنوان ژورنال: ChemBioChem
سال: 2018
ISSN: 1439-4227,1439-7633
DOI: 10.1002/cbic.201800493